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Plasmodium falciparum finds the winning combination
After 3 years of laboratory drug pressure in the presence of a picomolar inhibitor, the parasite Plasmodium falciparum developed a combination strategy of gene amplification and mutation to regain viability. The mutation observed led to a dysfunctional enzyme, but new research reveals the clever mec...
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| Publicado no: | J Biol Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8047455/ https://ncbi.nlm.nih.gov/pubmed/34237898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100526 |
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