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Plasmodium falciparum finds the winning combination

After 3 years of laboratory drug pressure in the presence of a picomolar inhibitor, the parasite Plasmodium falciparum developed a combination strategy of gene amplification and mutation to regain viability. The mutation observed led to a dysfunctional enzyme, but new research reveals the clever mec...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsman: Hengge, Alvan C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047455/
https://ncbi.nlm.nih.gov/pubmed/34237898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100526
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