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The phosphorylation of the Smad2/3 linker region by nemo-like kinase regulates TGF-β signaling
Smad2 and Smad3 (Smad2/3) are structurally similar proteins that primarily mediate the transforming growth factor-β (TGF-β) signaling responsible for driving cell proliferation, differentiation, and migration. The dynamics of the Smad2/3 phosphorylation provide the key mechanism for regulating the T...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8047224/ https://ncbi.nlm.nih.gov/pubmed/33676893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100512 |
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