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Impact of clinical targeted sequencing on endocrine responsiveness in estrogen receptor-positive, HER2-negative metastatic breast cancer

Clinical targeted sequencing allows for the selection of patients expected to have a better treatment response, and reveals mechanisms of resistance to molecular targeted therapies based on actionable gene mutations. We underwent comprehensive genomic testing with either our original in-house CLHURC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hagio, Kanako, Amano, Toraji, Hayashi, Hideyuki, Takeshita, Takashi, Oshino, Tomohiro, Kikuchi, Junko, Ohhara, Yoshihito, Yabe, Ichiro, Kinoshita, Ichiro, Nishihara, Hiroshi, Yamashita, Hiroko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047009/
https://ncbi.nlm.nih.gov/pubmed/33854152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87645-6
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