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Pleiotropic consequences of metabolic stress on the major histocompatibility complex class II molecule antigen processing and presentation machinery

Hyperglycemia and hyperlipidemia are often observed in patients with Type II Diabetes (T2D) and related mouse models. One dysmetabolic biochemical consequence is the non-enzymatic reaction between sugars, lipids and proteins, favoring protein glycation, glycoxidation and lipoxidation. Here, we ident...

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מידע ביבליוגרפי
הוצא לאור ב:	Immunity
Main Authors:	Clement, Cristina C., Nanaware, Padma P., Yamazaki, Takahiro, Negroni, Maria Pia, Ramesh, Karthik, Morozova, Kateryna, Thangaswamy, Sangeetha, Graves, Austin, Kim, Hei Jung, Li, Tsai Wanxia, Vigano’, Marco, Soni, Rajesh K., Gadina, Massimo, Tse, Harley Y., Galluzzi, Lorenzo, Roche, Paul A., Denzin, Lisa K., Stern, Lawrence J., Santambrogio, Laura
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2021
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8046741/ https://ncbi.nlm.nih.gov/pubmed/33725478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.02.019
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Pleiotropic consequences of metabolic stress on the major histocompatibility complex class II molecule antigen processing and presentation machinery

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