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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy

Our understanding of how the RAS protein family, and in particular mutant KRAS promote metabolic dysregulation in cancer cells has advanced significantly over the last decade. In this Review, we discuss the metabolic reprogramming mediated by oncogenic RAS in cancer, and elucidating the underlying m...

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Detalhes bibliográficos
Publicado no:Nat Cancer
Main Authors: Mukhopadhyay, Suman, Vander Heiden, Matthew G., McCormick, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045781/
https://ncbi.nlm.nih.gov/pubmed/33870211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00184-x
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