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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy

Our understanding of how the RAS protein family, and in particular mutant KRAS promote metabolic dysregulation in cancer cells has advanced significantly over the last decade. In this Review, we discuss the metabolic reprogramming mediated by oncogenic RAS in cancer, and elucidating the underlying m...

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Bibliographic Details
Published in:Nat Cancer
Main Authors: Mukhopadhyay, Suman, Vander Heiden, Matthew G., McCormick, Frank
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045781/
https://ncbi.nlm.nih.gov/pubmed/33870211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00184-x
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