Prospective KIR genotype evaluation of hematopoietic cell donors is feasible with potential to benefit patients with AML

Donor KIR and recipient HLA combinations that minimize inhibition and favor activation of the NK repertoire are associated with improved outcomes after allogeneic hematopoietic cell transplantation (HCT) in patients with myeloid neoplasia. We prospectively evaluated a weighted donor ranking algorith...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Shaffer, Brian C., Le Luduec, Jean-Benoit, Park, Soo, Devlin, Sean, Archer, Anne, Davis, Eric, Cooper, Candice, Nhaissi, Melissa, Suri, Beth, Wells, Deborah, Tamari, Roni, Papadopoulos, Esperanza, Jakubowski, Ann A., Giralt, Sergio, Hsu, Katharine C.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2021
Sujets:
Hematopoiesis and Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045509/
https://ncbi.nlm.nih.gov/pubmed/33843984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002701
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