Prospective KIR genotype evaluation of hematopoietic cell donors is feasible with potential to benefit patients with AML

Donor KIR and recipient HLA combinations that minimize inhibition and favor activation of the NK repertoire are associated with improved outcomes after allogeneic hematopoietic cell transplantation (HCT) in patients with myeloid neoplasia. We prospectively evaluated a weighted donor ranking algorith...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Shaffer, Brian C., Le Luduec, Jean-Benoit, Park, Soo, Devlin, Sean, Archer, Anne, Davis, Eric, Cooper, Candice, Nhaissi, Melissa, Suri, Beth, Wells, Deborah, Tamari, Roni, Papadopoulos, Esperanza, Jakubowski, Ann A., Giralt, Sergio, Hsu, Katharine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045509/
https://ncbi.nlm.nih.gov/pubmed/33843984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002701
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