Prospective KIR genotype evaluation of hematopoietic cell donors is feasible with potential to benefit patients with AML

Donor KIR and recipient HLA combinations that minimize inhibition and favor activation of the NK repertoire are associated with improved outcomes after allogeneic hematopoietic cell transplantation (HCT) in patients with myeloid neoplasia. We prospectively evaluated a weighted donor ranking algorith...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Shaffer, Brian C., Le Luduec, Jean-Benoit, Park, Soo, Devlin, Sean, Archer, Anne, Davis, Eric, Cooper, Candice, Nhaissi, Melissa, Suri, Beth, Wells, Deborah, Tamari, Roni, Papadopoulos, Esperanza, Jakubowski, Ann A., Giralt, Sergio, Hsu, Katharine C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045509/
https://ncbi.nlm.nih.gov/pubmed/33843984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002701
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