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Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation

Children with Down syndrome develop early signs of clonal evolution that resemble traditional clonal hematopoiesis. Children with trisomy 21 who exhibit clonal hematopoiesis display cytokine and gene expression profiles indicative of disrupted immunity.

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Detaylı Bibliyografya
Yayımlandı:Blood Adv
Asıl Yazarlar: Liggett, L. Alexander, Galbraith, Matthew D., Smith, Keith P., Sullivan, Kelly D., Granrath, Ross E., Enriquez-Estrada, Belinda, Kinning, Kohl T., Shaw, Jessica R., Rachubinski, Angela L., Espinosa, Joaquin M., DeGregori, James
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045490/
https://ncbi.nlm.nih.gov/pubmed/33787858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003858
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