Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation

Children with Down syndrome develop early signs of clonal evolution that resemble traditional clonal hematopoiesis. Children with trisomy 21 who exhibit clonal hematopoiesis display cytokine and gene expression profiles indicative of disrupted immunity.

Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Liggett, L. Alexander, Galbraith, Matthew D., Smith, Keith P., Sullivan, Kelly D., Granrath, Ross E., Enriquez-Estrada, Belinda, Kinning, Kohl T., Shaw, Jessica R., Rachubinski, Angela L., Espinosa, Joaquin M., DeGregori, James
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Stimulus Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045490/
https://ncbi.nlm.nih.gov/pubmed/33787858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003858
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