Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma

Drug resistance and disease recurrence are important contributors for the poor prognosis of glioblastoma multiforme (GBM). Temozolomide (TMZ), the standard chemotherapy for GBM treatment, can methylate DNA and cause the formation of double-strand breaks (DSBs). X-ray repair cross complementing 5 (XR...

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Detaylı Bibliyografya
Yayımlandı:Oncol Lett
Asıl Yazarlar: Lee, I-Neng, Yang, Jen-Tsung, Huang, Cheng, Huang, Hsiu-Chen, Wu, Yu-Ping, Chen, Jui-Chieh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2021
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045174/
https://ncbi.nlm.nih.gov/pubmed/33868481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12704
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