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Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma

INTRODUCTION: Glioblastoma (GBM) is the most lethal primary malignant brain tumor in adults with poor survival due to acquired therapeutic resistance and rapid recurrence. Currently, the standard clinical strategy for glioma includes maximum surgical resection, radiotherapy, and temozolomide (TMZ) c...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Wang, Jia, Zuo, Jie, Wahafu, Alafate, Wang, Mao‐de, Li, Rui‐chun, Xie, Wan‐fu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053231/
https://ncbi.nlm.nih.gov/pubmed/31318172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13197
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