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Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma
Drug resistance and disease recurrence are important contributors for the poor prognosis of glioblastoma multiforme (GBM). Temozolomide (TMZ), the standard chemotherapy for GBM treatment, can methylate DNA and cause the formation of double-strand breaks (DSBs). X-ray repair cross complementing 5 (XR...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8045174/ https://ncbi.nlm.nih.gov/pubmed/33868481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12704 |
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