Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma

BACKGROUND: Angiogenesis is a crucial process in tumorigenesis and development. The role of exosomes derived from hepatocellular carcinoma (HCC) cells in angiogenesis has not been clearly elucidated. METHODS AND RESULTS: Exosomes were isolated from HCC cell lines (HCCLM3, MHCC97L, and PLC/RFP/5) by...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Dong, Shuang-Shuang, Dong, Dan-Dan, Yang, Zhang-Fu, Zhu, Gui-Qi, Gao, Dong-Mei, Chen, Jie, Zhao, Yan, Liu, Bin-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044774/
https://ncbi.nlm.nih.gov/pubmed/33869178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.633358
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