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Analysis of CCN2 promoter activity in PANC-1 cells: regulation by ras/MEK/ERK
Connective tissue growth factor (CTGF, CCN2) is overexpressed in pancreatic cancer. We mapped the minimal CCN2 promoter active in PANC-1 cells, a human pancreatic cancer cell line. Within this region, Sp1, BCE-1 and Ets elements were important for the activity of the CCN2 promoter. Constitutive hype...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Netherlands
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275873/ https://ncbi.nlm.nih.gov/pubmed/18481199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-007-0008-9 |
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