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Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters

Norepinephrine is a biogenic amine neurotransmitter that has widespread effects on alertness, arousal and pain sensation. Consequently, blockers of norepinephrine uptake have served as vital tools to treat depression and chronic pain. Here, we employ the Drosophila melanogaster dopamine transporter...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Pidathala, Shabareesh, Mallela, Aditya Kumar, Joseph, Deepthi, Penmatsa, Aravind
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044178/
https://ncbi.nlm.nih.gov/pubmed/33850134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22385-9
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