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Neurotransmitter and psychostimulant recognition by the dopamine transporter

Na(+)/Cl(−)-coupled biogenic amine transporters are the primary targets of therapeutic and abused drugs, ranging from antidepressants to the psychostimulants cocaine and amphetamines, and to their cognate substrates. Here we determine x-ray crystal structures of the Drosophila melanogaster dopamine...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Wang, Kevin H., Penmatsa, Aravind, Gouaux, Eric
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469479/
https://ncbi.nlm.nih.gov/pubmed/25970245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14431
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