Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has a regulatory role in this context. Here, we used...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Goldsmith, Chloe, Rodríguez-Aguilera, Jesús Rafael, El-Rifai, Ines, Jarretier-Yuste, Adrien, Hervieu, Valérie, Raineteau, Olivier, Saintigny, Pierre, Chagoya de Sánchez, Victoria, Dante, Robert, Ichim, Gabriel, Hernandez-Vargas, Hector
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044111/
https://ncbi.nlm.nih.gov/pubmed/33850190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87457-8
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