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Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has a regulatory role in this context. Here, we used...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Goldsmith, Chloe, Rodríguez-Aguilera, Jesús Rafael, El-Rifai, Ines, Jarretier-Yuste, Adrien, Hervieu, Valérie, Raineteau, Olivier, Saintigny, Pierre, Chagoya de Sánchez, Victoria, Dante, Robert, Ichim, Gabriel, Hernandez-Vargas, Hector
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044111/
https://ncbi.nlm.nih.gov/pubmed/33850190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87457-8
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