The protein kinase Ire1 impacts pathogenicity of Candida albicans by regulating homeostatic adaptation to endoplasmic reticulum stress

The unfolded protein response (UPR), crucial for the maintenance of endoplasmic reticulum (ER) homeostasis, is tied to the regulation of multiple cellular processes in pathogenic fungi. Here, we show that Candida albicans relies on an ER‐resident protein, inositol‐requiring enzyme 1 (Ire1) for sensi...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Sircaik, Shabnam, Román, Elvira, Bapat, Priyanka, Lee, Keunsook K., Andes, David R., Gow, Neil A. R., Nobile, Clarissa J., Pla, Jesús, Panwar, Sneh Lata
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044019/
https://ncbi.nlm.nih.gov/pubmed/33403715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13307
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