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Mitochondria Influence CDR1 Efflux Pump Activity, Hog1-Mediated Oxidative Stress Pathway, Iron Homeostasis, and Ergosterol Levels in Candida albicans

Mitochondrial dysfunction in Candida albicans is known to be associated with drug susceptibility, cell wall integrity, phospholipid homeostasis, and virulence. In this study, we deleted CaFZO1, a key component required during biogenesis of functional mitochondria. Cells with FZO1 deleted displayed f...

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Autors principals: Thomas, Edwina, Roman, Elvira, Claypool, Steven, Manzoor, Nikhat, Pla, Jesús, Panwar, Sneh Lata
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811284/
https://ncbi.nlm.nih.gov/pubmed/23979757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00889-13
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