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Mitochondria Influence CDR1 Efflux Pump Activity, Hog1-Mediated Oxidative Stress Pathway, Iron Homeostasis, and Ergosterol Levels in Candida albicans

Mitochondrial dysfunction in Candida albicans is known to be associated with drug susceptibility, cell wall integrity, phospholipid homeostasis, and virulence. In this study, we deleted CaFZO1, a key component required during biogenesis of functional mitochondria. Cells with FZO1 deleted displayed f...

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Detalhes bibliográficos
Main Authors: Thomas, Edwina, Roman, Elvira, Claypool, Steven, Manzoor, Nikhat, Pla, Jesús, Panwar, Sneh Lata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811284/
https://ncbi.nlm.nih.gov/pubmed/23979757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00889-13
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