Nerve growth factor (NGF) pathway biomarkers in Down syndrome prior to and after the onset of clinical Alzheimer's disease: A paired CSF and plasma study

BACKGROUND: The discovery that nerve growth factor (NGF) metabolism is altered in Down syndrome (DS) and Alzheimer's disease (AD) brains offered a framework for the identification of novel biomarkers signalling NGF deregulation in AD pathology. METHODS: We examined levels of NGF pathway protein...

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Bibliografiske detaljer
Udgivet i:Alzheimers Dement
Main Authors: Pentz, Rowan, Iulita, M. Florencia, Ducatenzeiler, Adriana, Videla, Laura, Benejam, Bessy, Carmona‐Iragui, María, Blesa, Rafael, Lleó, Alberto, Fortea, Juan, Cuello, A. Claudio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043977/
https://ncbi.nlm.nih.gov/pubmed/33226181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12229
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