Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease

INTRODUCTION: People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. METHODS: Noradrenaline, adrenaline, and their metabolite 3-methoxy-4-hydroxyphen...

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Udgivet i:Alzheimers Dement (Amst)
Main Authors: Dekker, Alain D., Vermeiren, Yannick, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Gelpi, Ellen, Aerts, Tony, Van Dam, Debby, Fernández, Susana, Lleó, Alberto, Videla, Sebastian, Sieben, Anne, Martin, Jean-Jacques, Blesa, Rafael, Fortea, Juan, De Deyn, Peter P.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
CSF Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956808/
https://ncbi.nlm.nih.gov/pubmed/29780859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.11.001
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