Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease

INTRODUCTION: People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. METHODS: Noradrenaline, adrenaline, and their metabolite 3-methoxy-4-hydroxyphen...

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Veröffentlicht in:Alzheimers Dement (Amst)
Hauptverfasser: Dekker, Alain D., Vermeiren, Yannick, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Gelpi, Ellen, Aerts, Tony, Van Dam, Debby, Fernández, Susana, Lleó, Alberto, Videla, Sebastian, Sieben, Anne, Martin, Jean-Jacques, Blesa, Rafael, Fortea, Juan, De Deyn, Peter P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
CSF Biomarkers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956808/
https://ncbi.nlm.nih.gov/pubmed/29780859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.11.001
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