Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

Alzheimer’s disease (AD) is the most prevalent form of dementia and is characterized by abnormal extracellular aggregates of amyloid-β and intraneuronal hyperphosphorylated tau tangles and neuropil threads. Microglia, the tissue-resident macrophages of the central nervous system (CNS), are important...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol
Autori principali: Gerrits, Emma, Brouwer, Nieske, Kooistra, Susanne M., Woodbury, Maya E., Vermeiren, Yannick, Lambourne, Mirjam, Mulder, Jan, Kummer, Markus, Möller, Thomas, Biber, Knut, Dunnen, Wilfred F. A. den, De Deyn, Peter P., Eggen, Bart J. L., Boddeke, Erik W. G. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2021
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043951/
https://ncbi.nlm.nih.gov/pubmed/33609158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02263-w
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