Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue

Microglia are the tissue-resident macrophages of the central nervous system (CNS). Recent studies based on bulk and single-cell RNA sequencing in mice indicate high relevance of microglia with respect to risk genes and neuro-inflammation in Alzheimer’s disease (AD). Here, we investigated microglia t...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Alsema, Astrid M., Jiang, Qiong, Kracht, Laura, Gerrits, Emma, Dubbelaar, Marissa L., Miedema, Anneke, Brouwer, Nieske, Hol, Elly M., Middeldorp, Jinte, van Dijk, Roland, Woodbury, Maya, Wachter, Astrid, Xi, Simon, Möller, Thomas, Biber, Knut P., Kooistra, Susanne M., Boddeke, Erik W. G. M., Eggen, Bart J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655794/
https://ncbi.nlm.nih.gov/pubmed/33192286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00134
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