Gut microbiota-specific IgA(+) B cells traffic to the CNS in active multiple sclerosis

Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a central nervous system (CNS) autoimmune disease. Immunoglobulin A (IgA) is a key regulator at the mucosal interface. However, whether gut microbiota shape IgA responses and...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Immunol
المؤلفون الرئيسيون: Pröbstel, Anne-Katrin, Zhou, Xiaoyuan, Baumann, Ryan, Wischnewski, Sven, Kutza, Michael, Rojas, Olga L., Sellrie, Katrin, Bischof, Antje, Kim, Kicheol, Ramesh, Akshaya, Dandekar, Ravi, Greenfield, Ariele L., Schubert, Ryan D., Bisanz, Jordan E., Vistnes, Stephanie, Khaleghi, Khashayar, Landefeld, James, Kirkish, Gina, Liesche-Starnecker, Friederike, Ramaglia, Valeria, Singh, Sneha, Tran, Edwina B., Barba, Patrick, Zorn, Kelsey, Oechtering, Johanna, Forsberg, Karin, Shiow, Lawrence R., Henry, Roland G., Graves, Jennifer, Cree, Bruce A. C., Hauser, Stephen L., Kuhle, Jens, Gelfand, Jeffrey M., Andersen, Peter M., Schlegel, Jürgen, Turnbaugh, Peter J., Seeberger, Peter H., Gommerman, Jennifer L., Wilson, Michael R., Schirmer, Lucas, Baranzini, Sergio E.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2020
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043673/
https://ncbi.nlm.nih.gov/pubmed/33219152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abc7191
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