Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer

PURPOSE: Aggressive variant prostate cancer (AVPC) represents a clinical subset distinguished by therapy resistance and poor prognosis, linked to combined losses of the tumor suppressor genes (TSG) PTEN, RB1, and TP53. Circulating tumor cells (CTC) provide a minimally invasive opportunity for identi...

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Publicado en:Clin Cancer Res
Autores principales: Malihi, Paymaneh D., Graf, Ryon P., Rodriguez, Angel, Ramesh, Naveen, Lee, Jerry, Sutton, Ramsay, Jiles, Rhett, Velasco, Carmen Ruiz, Sei, Emi, Kolatkar, Anand, Logothetis, Christopher, Navin, Nicholas E., Corn, Paul, Aparicio, Ana M., Dittamore, Ryan, Hicks, James, Kuhn, Peter, Zurita, Amado J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043601/
https://ncbi.nlm.nih.gov/pubmed/32341031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-4100
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