Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer

PURPOSE: Aggressive variant prostate cancer (AVPC) represents a clinical subset distinguished by therapy resistance and poor prognosis, linked to combined losses of the tumor suppressor genes (TSG) PTEN, RB1, and TP53. Circulating tumor cells (CTC) provide a minimally invasive opportunity for identi...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Principais autores: Malihi, Paymaneh D., Graf, Ryon P., Rodriguez, Angel, Ramesh, Naveen, Lee, Jerry, Sutton, Ramsay, Jiles, Rhett, Velasco, Carmen Ruiz, Sei, Emi, Kolatkar, Anand, Logothetis, Christopher, Navin, Nicholas E., Corn, Paul, Aparicio, Ana M., Dittamore, Ryan, Hicks, James, Kuhn, Peter, Zurita, Amado J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043601/
https://ncbi.nlm.nih.gov/pubmed/32341031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-4100
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