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NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations

Natural killer (NK) cells, the primary effector cells of the innate immune system, utilize multiple strategies to recognize tumor cells by (1) detecting the presence of activating receptor ligands, which are often upregulated in cancer; (2) targeting cells that have a loss of major histocompatibilit...

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Publicat a:Transplant Cell Ther
Autors principals: Sanchez, Carlos E., Dowlati, Ehsan P., Geiger, Ashley E., Chaudhry, Kajal, Tovar, Matthew A., Bollard, Catherine M., Cruz, Conrad Russell Y.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043250/
https://ncbi.nlm.nih.gov/pubmed/33007496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2020.09.030
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