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NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations

Natural killer (NK) cells, the primary effector cells of the innate immune system, utilize multiple strategies to recognize tumor cells by (1) detecting the presence of activating receptor ligands, which are often upregulated in cancer; (2) targeting cells that have a loss of major histocompatibilit...

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Detalles Bibliográficos
Publicado en:Transplant Cell Ther
Main Authors: Sanchez, Carlos E., Dowlati, Ehsan P., Geiger, Ashley E., Chaudhry, Kajal, Tovar, Matthew A., Bollard, Catherine M., Cruz, Conrad Russell Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043250/
https://ncbi.nlm.nih.gov/pubmed/33007496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2020.09.030
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