Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19

[Image: see text] The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has prompted researchers to pivot their efforts to finding antiviral compounds and vaccines. In this study, we focused on the human host cell transmembrane protease serine 2 (TMPRSS2), which plays an importan...

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Foilsithe in:ACS Pharmacol Transl Sci
Main Authors: Hu, Xin, Shrimp, Jonathan H., Guo, Hui, Xu, Miao, Chen, Catherine Z., Zhu, Wei, Zakharov, Alexey V., Jain, Sankalp, Shinn, Paul, Simeonov, Anton, Hall, Matthew D., Shen, Min
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2021
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043206/
https://ncbi.nlm.nih.gov/pubmed/34136758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00221
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