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TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform
The COVID-19 pandemic has highlighted the need for new antiviral targets, as many of the currently approved drugs have proven ineffective against mitigating SARS-CoV-2 infections. The host transmembrane serine protease TMPRSS2 is a highly promising antiviral target, as it plays a direct role in prim...
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| Publicado no: | bioRxiv |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8010734/ https://ncbi.nlm.nih.gov/pubmed/33791707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.22.436465 |
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