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Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BK(Ca) Channels to Vasorelaxant Mechanisms
Background: The current study presents the novel angiotensin II receptor blocker fluorophenyl benzimidazole (FPD) as an antihypertensive agent in the SHR model of hypertension. We investigated the role of cGMP, voltage-dependent L-type calcium channels, and BK(Ca) channels in the vasorelaxant mechan...
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| Pubblicato in: | Front Pharmacol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8042648/ https://ncbi.nlm.nih.gov/pubmed/33859561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.611109 |
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