Behavioral Consequences of a Combination of Gad1 Haplodeficiency and Adolescent Exposure to an NMDA Receptor Antagonist in Long-Evans Rats

Glutamate decarboxylase 67-kDa isoform (GAD67), which is encoded by the GAD1 gene, is one of the key enzymes that produce GABA. The reduced expression of GAD67 has been linked to the pathophysiology of schizophrenia. Additionally, the excitatory glutamatergic system plays an important role in the de...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: Fujihara, Kazuyuki, Sato, Takumi, Higeta, Kazuya, Miyasaka, Yoshiki, Mashimo, Tomoji, Yanagawa, Yuchio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042137/
https://ncbi.nlm.nih.gov/pubmed/33859565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.646088
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