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Behavioral Consequences of a Combination of Gad1 Haplodeficiency and Adolescent Exposure to an NMDA Receptor Antagonist in Long-Evans Rats

Glutamate decarboxylase 67-kDa isoform (GAD67), which is encoded by the GAD1 gene, is one of the key enzymes that produce GABA. The reduced expression of GAD67 has been linked to the pathophysiology of schizophrenia. Additionally, the excitatory glutamatergic system plays an important role in the de...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Fujihara, Kazuyuki, Sato, Takumi, Higeta, Kazuya, Miyasaka, Yoshiki, Mashimo, Tomoji, Yanagawa, Yuchio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042137/
https://ncbi.nlm.nih.gov/pubmed/33859565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.646088
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