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Most non-canonical proteins uniquely populate the proteome or immunopeptidome

Combining RNA sequencing, ribosome profiling, and mass spectrometry, we elucidate the contribution of non-canonical translation to the proteome and major histocompatibility complex (MHC) class I immunopeptidome. Remarkably, of 14,498 proteins identified in three human B cell lymphomas, 2,503 are non...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Cuevas, Maria Virginia Ruiz, Hardy, Marie-Pierre, Hollý, Jaroslav, Bonneil, Éric, Durette, Chantal, Courcelles, Mathieu, Lanoix, Joël, Côté, Caroline, Staudt, Louis M., Lemieux, Sébastien, Thibault, Pierre, Perreault, Claude, Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040094/
https://ncbi.nlm.nih.gov/pubmed/33691108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108815
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