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MHC class I–associated peptides derive from selective regions of the human genome

MHC class I–associated peptides (MAPs) define the immune self for CD8(+) T lymphocytes and are key targets of cancer immunosurveillance. Here, the goals of our work were to determine whether the entire set of protein-coding genes could generate MAPs and whether specific features influence the abilit...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pearson, Hillary, Daouda, Tariq, Granados, Diana Paola, Durette, Chantal, Bonneil, Eric, Courcelles, Mathieu, Rodenbrock, Anja, Laverdure, Jean-Philippe, Côté, Caroline, Mader, Sylvie, Lemieux, Sébastien, Thibault, Pierre, Perreault, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127664/
https://ncbi.nlm.nih.gov/pubmed/27841757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88590
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