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Impact of Mitochondrial Targeting Antibiotics on Mitochondrial Function and Proliferation of Cancer Cells

[Image: see text] Some marketed antibiotics can cause mitochondria dysfunction via inhibition of the mitochondrial translation process. There is great interest in exploiting such effects within a cancer setting. To enhance accumulation of antibiotics within the mitochondria of cancer cells, and ther...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Cochrane, Edward J., Hulit, James, Lagasse, Franz P., Lechertier, Tanguy, Stevenson, Brett, Tudor, Corina, Trebicka, Diana, Sparey, Tim, Ratcliffe, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040039/
https://ncbi.nlm.nih.gov/pubmed/33859798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00632
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