Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction

T-cell products derived from third-party donors are clinically applied, but harbor the risk of off-target toxicity via induction of allo-HLA cross-reactivity directed against mismatched alleles. We used third-party donor-derived virus-specific T cells as model to investigate whether virus-specificit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Huisman, Wesley, Leboux, Didier A. T., van der Maarel, Lieve E., Hageman, Lois, Amsen, Derk, Falkenburg, J. H. Frederik, Jedema, Inge
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039299/
https://ncbi.nlm.nih.gov/pubmed/33854504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.630440
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados