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Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition

18 transfected cell lines were generated that expressed distinct DQ molecules related to the serologically defined HLA-DQw3 specificity. These transfectants were constructed using site-directed mutagenesis to introduce nucleotide substitutions into DQ3.2 beta cDNA, followed by retrovirus-mediated ge...

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Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1990
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187655/
https://ncbi.nlm.nih.gov/pubmed/2104922
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