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RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field

SIMPLE SUMMARY: Integrins, a superfamily of cell adhesion receptors, were extensively investigated as therapeutic targets over the last decades, motivated by their multiple functions, e.g., in cancer (progression, metastasis, angiogenesis), sepsis, fibrosis, and viral infections. Although integrin-t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Ludwig, Beatrice S., Kessler, Horst, Kossatz, Susanne, Reuning, Ute
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038522/
https://ncbi.nlm.nih.gov/pubmed/33916607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071711
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