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A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variet...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Kapp, Tobias G., Rechenmacher, Florian, Neubauer, Stefanie, Maltsev, Oleg V., Cavalcanti-Adam, Elisabetta A., Zarka, Revital, Reuning, Ute, Notni, Johannes, Wester, Hans-Jürgen, Mas-Moruno, Carlos, Spatz, Joachim, Geiger, Benjamin, Kessler, Horst
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225454/
https://ncbi.nlm.nih.gov/pubmed/28074920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39805
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