A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variet...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kapp, Tobias G., Rechenmacher, Florian, Neubauer, Stefanie, Maltsev, Oleg V., Cavalcanti-Adam, Elisabetta A., Zarka, Revital, Reuning, Ute, Notni, Johannes, Wester, Hans-Jürgen, Mas-Moruno, Carlos, Spatz, Joachim, Geiger, Benjamin, Kessler, Horst
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225454/
https://ncbi.nlm.nih.gov/pubmed/28074920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39805
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