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RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field

SIMPLE SUMMARY: Integrins, a superfamily of cell adhesion receptors, were extensively investigated as therapeutic targets over the last decades, motivated by their multiple functions, e.g., in cancer (progression, metastasis, angiogenesis), sepsis, fibrosis, and viral infections. Although integrin-t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ludwig, Beatrice S., Kessler, Horst, Kossatz, Susanne, Reuning, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038522/
https://ncbi.nlm.nih.gov/pubmed/33916607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071711
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