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RTK Inhibitors in Melanoma: From Bench to Bedside
SIMPLE SUMMARY: Receptor tyrosine kinases (RTKs) have long been demonstrated to play key roles in melanoma development. RTK activation requires dimerization and intracellular tyrosine trans-phosphorylation leading to downstream signaling pathways activation. As RTKs show different structures, mechan...
Sparad:
| I publikationen: | Cancers (Basel) |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
MDPI
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8038208/ https://ncbi.nlm.nih.gov/pubmed/33918490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071685 |
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