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RTK Inhibitors in Melanoma: From Bench to Bedside
SIMPLE SUMMARY: Receptor tyrosine kinases (RTKs) have long been demonstrated to play key roles in melanoma development. RTK activation requires dimerization and intracellular tyrosine trans-phosphorylation leading to downstream signaling pathways activation. As RTKs show different structures, mechan...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8038208/ https://ncbi.nlm.nih.gov/pubmed/33918490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071685 |
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