The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma

Radiotherapy (RT) in patients with melanoma historically showed suboptimal results, because the disease is often radioresistant due to various mechanisms such as scavenging free radicals by thiols, pigmentary machinery, or enhanced DNA repair. However, radiotherapy has been utilized as adjuvant ther...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Krayem, Mohammad, Sabbah, Malak, Najem, Ahmad, Wouters, An, Lardon, Filip, Simon, Stephane, Sales, François, Journe, Fabrice, Awada, Ahmad, Ghanem, Ghanem E., Van Gestel, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721382/
https://ncbi.nlm.nih.gov/pubmed/31374895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081093
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