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NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells

SIMPLE SUMMARY: Development of resistance to chemotherapeutics during the treatment of human cancers is a serious problem in the clinic, resulting in a poor treatment outcome and survival. It is believed that overexpression of ABC efflux proteins (e.g., P-gp/ABCB1, BCRP/ABCG2 and MRP/ABCC1) on the t...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Sinha, Birandra K., Perera, Lalith, Cannon, Ronald E.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038154/
https://ncbi.nlm.nih.gov/pubmed/33918289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071680
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