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Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Intracellular superoxide dismutases (SODs) maintain tissue homeostasis via superoxide metabolism. We previously reported that intracellular reactive oxygen species (ROS), including superoxide accumulation caused by cytoplasmic SOD (SOD1) or mitochondrial SOD (SOD2) insufficiency, induced p53 activat...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Watanabe, Kenji, Shibuya, Shuichi, Ozawa, Yusuke, Toda, Toshihiko, Shimizu, Takahiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037821/
https://ncbi.nlm.nih.gov/pubmed/33805584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073548
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