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Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Intracellular superoxide dismutases (SODs) maintain tissue homeostasis via superoxide metabolism. We previously reported that intracellular reactive oxygen species (ROS), including superoxide accumulation caused by cytoplasmic SOD (SOD1) or mitochondrial SOD (SOD2) insufficiency, induced p53 activat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Watanabe, Kenji, Shibuya, Shuichi, Ozawa, Yusuke, Toda, Toshihiko, Shimizu, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037821/
https://ncbi.nlm.nih.gov/pubmed/33805584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073548
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